Full Project – EFFECT OF TELFERIA OCCIDENTALIS AND VERNONIA AMYGDALINA ON ANTIOXIDANTS AND MALONDIALDEHYDE IN HEART, PLASMA AND BRAIN IN HIGH SUCROSE DIET FED RATS

Click here to Get this Complete Project Chapter 1-5

ABSTRACT

This present study was aimed at investigating the effect of the processing methods (Juice and Shaft) on oxidative stress induced by high sucrose diets on Catalase, Superoxide Dismutase (SOD) and Malondiadehyde (MDA) in the heart, brain and plasma. The juice and shaft extract of Telferia occidentalis(Ugwu) and Vernonia amygdalina (Ewuro) vegetables were processed and were administered alongside high sucrose. 104 albino rats (male) of wistar strain, weighing between 60-175g were bought and were divided into two groups, namely, Group I (control group), Group II (experimental group). The animals were weighed after acclimatization and were administered treatment according to their body weight. The Control group were fed with rat chow and the experimental group were fed with 40% sucrose palletized with their diet (rat chow). Each group were subdivided into four groups, Group 1: NOR (Normal Rat chow), NUJ (Normal Ugwu Juice), NUS (Normal Ugwu Shaft), NEJ (Normal Ewuro Juice), NES (Normal Ewuro Shaft) and the Group II : HSO (High Sucrose only), HUJ (High Sucrose Ugwu Juice), HUS (High Sucrose Ugwu Shaft), HEJ (High Sucrose Ewuro Juice) and HES (High Sucrose Ewuro Shaft). The result shows that high sucrose diets does not have an effect on the antioxidants as the levels of catalase in the brain, heart and plasma were within the normal range, except for High Sucrose Ewuro Shaft which excessively increased the level of catalase in the heart(P < 0.05). Also, the levels of malondiadehyde and superoxide dismutase in the brain, heart and plasma were all within the normal level, after administration of all the diets (P < 0.05).

TABLE OF CONTENTS

CHAPTER ONE

1.0     Introduction

CHAPTER TWO

2.0     Cardiovascular disease

2.1     Sucrose

2.1.1  Properties of sucrose

2.1.2  Metabolism of sucrose

2.1.3  Sucrose consumption and health

2.2     Plants

2.2.1  Telferia occidentalis (Ugwu)

2.2.2  Vernonia amygdalina (Efo ewuro)

2.3     Oxidative stress

2.4     Antioxidants

2.4.1  Superoxide dismutase

2.4.2  Catalase

2.4.3  Malondialdehyde

CHAPTER THREE

3.0     Materials and Methods

3.1     Materials

3.2     Chemical reagents

3.3     Methods

3.3.1  Diet composition

3.3.2  Feeding and grouping of animals

3.3.3  Animal Sacrifice

3.3.4  Homogenate preparation

3.4     Biochemical analysis

3.5     Statistical Analysis

CHAPTER FOUR

4.0     Results

CHAPTER FIVE

5.0     Discussion, Conclusion and Recommendation

5.1     Discussion

5.2     Conclusion

5.3     Recommendation

References

Get the Complete Project

This is a premium project material and the complete research project plus questionnaires and references can be gotten at an affordable rate of N3,000 for Nigerian clients and $8 for International clients.

Click here to Get this Complete Project Chapter 1-5

You can also check other Research Project here:

1. Accounting Research Project
2. Adult Education
3. Agricultural Science
4. Banking & Finance
5. Biblical Theology & CRS
6. Biblical Theology and CRS
7. Biology Education
8. Business Administration
9. Computer Engineering Project
10. Computer Science 2
11. Criminology Research Project
12. Early Childhood Education
13. Economic Education
14. Education Research Project
15. Educational Administration and Planning Research Project
16. English
17. English Education
18. Entrepreneurship
19. Environmental Sciences Research Project
20. Guidance and Counselling Research Project
21. History Education
22. Human Kinetics and Health Education
23. Management
24. Maritime and Transportation
25. Marketing
26. Marketing Research Project 2
27. Mass Communication
28. Mathematics Education
29. Medical Biochemistry Project
30. Organizational Behaviour

32    Other Projects pdf doc

33. Political Science
34. Psychology
35. Public Administration
36. Public Health Research Project
37. More Research Project
38. Transportation Management
39. Nursing

Education

Full Project – EFFECT OF TELFERIA OCCIDENTALIS AND VERNONIA AMYGDALINA ON ANTIOXIDANTS AND MALONDIALDEHYDE IN HEART, PLASMA AND BRAIN IN HIGH SUCROSE DIET FED RATS